Hydrochloric Acid → HCID 69677733, compound

HRID 584222Notes

Reaction equation

HRID 584222 reaction equation
C([N:4]([C:10]1[CH:15]=[CH:14][C:13]([CH3:16])=[C:12]([CH3:17])[CH:11]=1)[C@@H:5]([C:7]([OH:9])=[O:8])[CH3:6])(=O)C.[ClH:18]>C(O)(=O)C>[ClH:18].[CH3:17][C:12]1[CH:11]=[C:10]([NH:4][C@@H:5]([C:7]([OH:9])=[O:8])[CH3:6])[CH:15]=[CH:14][C:13]=1[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54314221HCID 54314221, compound

Product 1

HCID 69677733HCID 69677733, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of N-acetyl-3,4-dimethylphenyl-D-alanine (5.0 g) in a mixture of concentrated hydrochloric acid (50 ml) and acetic acid (50 ml) was stirred under reflux for 20 hours. After being cooled to room temperature, the resulting precipitates were collected by filtration and washed with ethyl acetate to give colorless crystals of 3,4-dimethylphenyl-D-alanine hydrochloride (3.75 g).

Workup

  1. temperatureunder reflux for 20 hours
  2. customthe resulting precipitates
  3. filtrationwere collected by filtration
  4. washwashed with ethyl acetate

Sources & evidence

ORD record
ord-bb7b2290d4244cb09d367f8f0cbc1ddf
Source dataset
uspto-grants-2005_08
Patent number
US06924278B2

Reaction notes

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