HRID584325

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CCC(=O)c1ccc(-c2cc(N(Cc3ccc(COC(=O)c4ccccc4)c(COC(=O)c4ccccc4)c3)C(=O)OC(C)(C)C)ccc2C)c(C)c1

HCID69792889

未命名化合物

PRODUCTS

生成物

结构：CCC(=O)c1ccc(-c2cc(NCc3ccc(COC(=O)c4ccccc4)c(COC(=O)c4ccccc4)c3)ccc2C)c(C)c1

HCID69792603

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

1 g (1.4 mmol) of 2-benzoyloxymethyl-5-{[tert-butoxycarbonyl(6,2′-dimethyl-4′-propionyl-biphenyl-3-yl)amino]methyl}benzyl benzoate are dissolved in 50 ml of dichloromethane. 1,1 ml (14 mmol) of trifluoroacetic acid are added and the medium is stirred at room temperature for 6 hours. After extraction with water/dichloromethane, the desired product is obtained in the form of a yellowish oil (m=820 mg, Y=95%).

WORKUP

后处理

extractionAfter extraction with water/dichloromethane

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-640904a968d24a97a6d173a3a71282b8
来源数据集: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06924400B2
来源说明: uspto-grants-2005_08

反应 SMILES

[C:1]([O:9][CH2:10][C:11]1[CH:16]=[C:15]([CH2:17][N:18](C(OC(C)(C)C)=O)[C:19]2[CH:20]=[C:21]([C:26]3[CH:31]=[CH:30][C:29]([C:32](=[O:35])[CH2:33][CH3:34])=[CH:28][C:27]=3[CH3:36])[C:22]([CH3:25])=[CH:23][CH:24]=2)[CH:14]=[CH:13][C:12]=1[CH2:44][O:45][C:46](=[O:53])[C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.FC(F)(F)C(O)=O>ClCCl>[C:1]([O:9][CH2:10][C:11]1[CH:16]=[C:15]([CH2:17][NH:18][C:19]2[CH:20]=[C:21]([C:26]3[CH:31]=[CH:30][C:29]([C:32](=[O:35])[CH2:33][CH3:34])=[CH:28][C:27]=3[CH3:36])[C:22]([CH3:25])=[CH:23][CH:24]=2)[CH:14]=[CH:13][C:12]=1[CH2:44][O:45][C:46](=[O:53])[C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1