Phenylboronic Acid → HCID 69655034, compound

HRID 584579Notes

Reaction equation

HRID 584579 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15][CH2:14][C:13]=2Br)=[CH:8][CH:7]=1.[C:24]1(B(O)O)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>CC#N>[CH3:1][O:2][C:3](=[O:23])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15][CH2:14][C:13]=2[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 66827Phenylboronic AcidHCID 74063892HCID 74063892, compound

Product 1

HCID 69655034HCID 69655034, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared from the coupling of 2k and benzene boronic acid, (R6—Ph)B(OH)2 where R6=H, by the general method described for example 2d. Yield 50%; APcI m/z: 408 (M+H+CH3CN+, 100%).

Sources & evidence

ORD record
ord-c1b3acf43cf14361864746c92ce19e9d
Source dataset
uspto-grants-2005_08
Patent number
US06927224B2

Reaction notes

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