反应详情

温度

55 °C

48% aqueous HBr (8.8 M) (3.4 ml, 30 mmol) was slowly added to a stirred solution of 3,4-dichloroacetophenone (1.89 g, 10 mmol) in DMSO (17 ml). The solution was stirred in an open flask at 55° C. for 24 hours. The solution was poured onto ice, the solid product was filtered, washed with water, and redissolved in ethanol (18 ml). 4,5-Dinitro-1,2-phenylene-diamine (890 mg, 4.5 mmol) was added and the mixture was heated to reflux for 4 hours.

1. additionThe solution was poured onto ice
2. filtrationthe solid product was filtered
3. washwashed with water
4. dissolutionredissolved in ethanol (18 ml)
5. temperaturethe mixture was heated
6. temperatureto reflux for 4 hours