HCID 17957483, compound → HCID 10160726, compound

HRID 584922Notes

Reaction equation

HRID 584922 reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH2:31][CH3:32])[C:23](=[O:30])[C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1.O=C1NC(=O)C(CC2C=CC(C3C=CC=C(CC4C=CC=CC=4C(NCC)=O)C=3)=CC=2)S1>C1COCC1>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[CH:4]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH2:31][CH3:32])[C:23](=[O:30])[C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH:16]=3)=[CH:13][CH:14]=2)[S:3]1

Participants

4

Reactant 2

HCID 17957483HCID 17957483, compoundHCID 86591250HCID 86591250, compound

Product 1

HCID 10160726HCID 10160726, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to that of Example 1(g), starting with 300 mg (0.7 mmol) of N-[4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]-N-ethylbenzamide in 10 ml THF, 150 mg (50%) of N-[4′-(2,4-dioxothiazolidin-5-ylmethyl)biphenyl-3-ylmethyl-N-ethylbenzamide, with a melting point of 157° C., are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-d4ce13bff9b347a0ba4e8a41fdafff85
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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