HCID 131725063, compound → HCID 10159792, compound

HRID 584940Notes

Reaction equation

HRID 584940 reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][C:22]([N:24]([CH3:31])[C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)=[O:23])[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1>C(OCC)(=O)C.C(O)C>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[CH:4]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][C:22]([N:24]([CH3:31])[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=4)=[O:23])[CH:16]=3)=[CH:13][CH:14]=2)[S:3]1

Participants

4

Reactant 1

HCID 131725063HCID 131725063, compound

Product 1

HCID 10159792HCID 10159792, compoundYield 60%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

In a manner similar to that of Example 1(g), starting with 1.1 g (2.6 mmol) of 2-[4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-yl]-N-methyl-N-phenylacetamide in 20 ml of ethyl acetate and 20 ml of ethanol, 660 mg (60%) of the desired product, with a melting point of 158° C., are obtained.

Sources & evidence

ORD record
ord-c8159f4bf607495ab5132a09b6a20a46
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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