HCID 86591262, compound → HCID 10136671, compound

HRID 584950Notes

Reaction equation

HRID 584950 reaction equation
[CH2:1]([NH:8][C:9]([C:11]1[CH:12]=[C:13]([C:17]2[CH:22]=[CH:21][C:20]([CH:23]=[C:24]3[S:28][C:27](=[O:29])[NH:26][C:25]3=[O:30])=[CH:19][CH:18]=2)[CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CN(C)C=O>[CH2:1]([NH:8][C:9]([C:11]1[CH:12]=[C:13]([C:17]2[CH:22]=[CH:21][C:20]([CH2:23][CH:24]3[S:28][C:27](=[O:29])[NH:26][C:25]3=[O:30])=[CH:19][CH:18]=2)[CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 86591262HCID 86591262, compound

Product 1

HCID 10136671HCID 10136671, compoundYield 24%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a manner similar to that of Example 1(g), starting with 430 mg (1 mmol) of N-benzyl-4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-carboxamide in 7 ml of dimethylformamide, 100 mg (23%) of the desired product, with a melting point of 148° C., are obtained.

Sources & evidence

ORD record
ord-3ea0b1e7c897487db481f6662a4a82e1
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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