Ethyl formate → N-formyl-1-aminoundec-10-ene

HRID 585020Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12].[CH:13](OCC)=[O:14]>>[CH:13]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])=[O:14]

Participants

Reactant 2

HCID 8025Ethyl formate

HCID 11768976Undec-10-en-1-amine

Product 1

HCID 12039861N-formyl-1-aminoundec-10-eneYield 99%

Procedure

A solution of commercially available 1-aminoundec-10-ene (1 g) dissolved in ethyl formate (3.5 mL) was kept at 50° during 3 h. Evaporation of the solvent yielded 1.18 g of N-formyl-1-aminoundec-10-ene (yield: 99%).

Workup

customEvaporation of the solvent

Sources & evidence

ORD record: ord-a42b62b278b24ee6adee68a9f7463c74
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06929685B2

Reaction notes

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