Hydrochloric Acid → HCID 22340319, compound

Participants

Reaction Conditions

Reaction Steps

To the N-[2-(chloromethyl)-6-quinolinyl]acetamide hydrochloride (900 mg, 3.32 mmol) obtained in Reference Example 6 was added 5N hydrochloric acid (17 ml), and the mixture was stirred at 100° C. for 2 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was washed with tetrahydrofuran to obtain the titled compound (849 mg) as powders.

Provenance & Evidence