反应详情

温度

100 °C

A solution of the 1-[(6-methoxy-2-naphthyl)methyl]pyrrolidine (3.63 g, 15.0 mmol) obtained in Reference Example 21 in 48% hydrobromic acid (75 ml) was stirred at 100° C. for 6 hours. The reaction solution was diluted with water, the produced crystals were collected, and washed with water, tetrahydrofuran and diisopropyl ether to obtain the titled compound (2.45 g) as a colorless powder.

1. customthe produced crystals were collected
2. washwashed with water, tetrahydrofuran and diisopropyl ether