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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 585515Generated: October 31, 2026

Hydrochloric Acid → HCID 22337082, compound

https://huagongshe.com/reaction/585515

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86595792HCID 86595792—
ProductHCID 22337082HCID 22337082—

Reaction Steps

Starting with tert-butyl {3′-[(4-{[(5-chloro-2-thienyl)carbonyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-4-fluoro[1,1′-biphenyl]-3-yl}methylcarbamate, by treating the crude product with etheral hydrochloric acid solution, it is possible to obtain N-(2-{[3′-(aminomethyl)-4′-fluoro[1,1′-biphenyl]-3-yl]methyl}-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)-5-chloro-2-thiophenecarboxamide hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06933295B2
Source datasetuspto-grants-2005_08
ORD IDord-3319f691a9ca49e48d74a96f75029580
Source noteuspto-grants-2005_08