HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22337082, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86595792 | HCID 86595792 | — |
| Product | HCID 22337082 | HCID 22337082 | — |
Reaction Steps
Starting with tert-butyl {3′-[(4-{[(5-chloro-2-thienyl)carbonyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-4-fluoro[1,1′-biphenyl]-3-yl}methylcarbamate, by treating the crude product with etheral hydrochloric acid solution, it is possible to obtain N-(2-{[3′-(aminomethyl)-4′-fluoro[1,1′-biphenyl]-3-yl]methyl}-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)-5-chloro-2-thiophenecarboxamide hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933295B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-3319f691a9ca49e48d74a96f75029580 |
| Source note | uspto-grants-2005_08 |