HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Difluorobenzaldehyde → Methyl(S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-(2,3-difluorobenzylamino)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Difluorobenzaldehyde | HCID 137664 | — |
| Reactant | Ethyl(S)-3-[4-[2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethoxy]phenyl]-2-(4-fluorobenzylamino)propionate | HCID 12149026 | — |
| Product | Methyl(S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-(2,3-difluorobenzylamino)propionate | HCID 69732747 | — |
Reaction Steps
In the same manner as in Example 7, 253.2 mg of the title compound was obtained as colorless oil from 510.0 mg of Referential Compound 3 and 191 μL of 2,3-difluorobenzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933309B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-f81bb5740b584c95b518089db0d3a81e |
| Source note | uspto-grants-2005_08 |