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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 585740Generated: October 26, 2026

Potassium Carbonate → (S)-4-(tert-butoxycarbonylamino)thiochromane-7-carboxylic acid

https://huagongshe.com/reaction/585740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant(S)-4-(tert-butoxycarbonylamino)thiochromane-7-carboxylic acid methyl esterHCID 59089451—
Product(S)-4-(tert-butoxycarbonylamino)thiochromane-7-carboxylic acidHCID 5908945596.2%

Reaction Steps

By a similar reaction operation as in Starting Material Synthetic Example 6 using (S)-4-(tert-butoxycarbonylamino)thiochromane-7-carboxylic acid methyl ester (5.75 g) and potassium carbonate (4.91 g), the objective (S)-4-(tert-butoxycarbonylamino)thiochromane-7-carboxylic acid (5.29 g) was obtained as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06933305B2
Source datasetuspto-grants-2005_08
ORD IDord-bbd74c5ca5734e3b8858eecc2396b34d
Source noteuspto-grants-2005_08