HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-(Tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid methyl ester | HCID 20824509 | — |
| Product | 4-(Tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid | HCID 22337379 | 89.8% |
Reaction Steps
By a similar reaction operation as in Starting Material Synthetic Example 6 using 4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid methyl ester (2.80 g) and potassium carbonate (3.44 g), the objective 4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid (2.41 g) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933305B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-ef19413c7f024b5aa89f4246e42cbfa8 |
| Source note | uspto-grants-2005_08 |