Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 585751Generated: October 25, 2026

Potassium Carbonate → (S)-4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid

https://huagongshe.com/reaction/585751

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant(S)-4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid methyl esterHCID 59089450—
Product(S)-4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acidHCID 5908948577.9%

Reaction Steps

By a similar reaction operation as in Starting Material Synthetic Example 6 using (S)-4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid methyl ester (8.10 g) and potassium carbonate (9.94 g), the objective (S)-4-(tert-butoxycarbonylamino)-6-methylthiochromane-7-carboxylic acid (6.05 g) was obtained as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06933305B2
Source datasetuspto-grants-2005_08
ORD IDord-a6e00e5f2b4646359537347b20306ea9
Source noteuspto-grants-2005_08