反应详情

温度

110 °C

In the solution of 220 g(2 mol) of hydroquinone in 500 ml of glycol dibutyl ether, 140.5 g(1 mol) of benzoyl chloride was drop-added for one hour while agitating the solution at 110° C. The mixture was maintained at 110° C. for two hours, and diethylene glycol dibutyl ether was distilled under vacuum. 1 liter of methylene chloride was added to the reaction mixture, and the unreacted excess hydroquinone was filtered and collected (recovered amount: 110 g, recycled without any purification process). A desired mono benzoyl hydroquinone was obtained by evaporating the residue under vacuum. (Yield: 207.0 g(97%). mp: 160-162° C., 1H-NMR(300 MHz, CDCl3, ppm) 5.80 (br, 1H), 6.72 (d,2H), 6.89 (d, 2H), 7.44-7.48 (m, 1H), 7.49-7.56 (m, 1H), 8.16 (d, 2H).

1. temperatureThe mixture was maintained at 110° C. for two hours
2. distillationdiethylene glycol dibutyl ether was distilled under vacuum
3. addition1 liter of methylene chloride was added to the reaction mixture
4. filtrationthe unreacted excess hydroquinone was filtered
5. customcollected (
6. customrecovered amount