3-Chlorophenethylamine → HCID 22329680, compound

HRID 586156Notes

Reaction equation

HRID 586156 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][NH2:10])[CH:5]=[CH:6][CH:7]=1.[CH3:11][C:12]1[N:13]=[C:14]([CH2:35][CH2:36][CH3:37])[N:15]2[C:20]=1[C:19](N1C=NC=N1)=[N:18][C:17]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[O:32][CH2:33][CH3:34])=[N:16]2>C(N(CC)CC)C>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][NH:10][C:19]2[C:20]3=[C:12]([CH3:11])[N:13]=[C:14]([CH2:35][CH2:36][CH3:37])[N:15]3[N:16]=[C:17]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=3[O:32][CH2:33][CH3:34])[N:18]=2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 1393813-ChlorophenethylamineHCID 22329677HCID 22329677, compound

Product 1

HCID 22329680HCID 22329680, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent2×

Procedure

In a parallel synthetic run, 18.7 mg (0.12 mmol) of 2-(3-chlorophenyl)ethylamine are introduced into a reaction vessel and treated with 1,2-dichloroethane solutions of Example 39A and triethylamine. The amount added is 29.1 mg (0.08 mmol; solution: 0.08 mol/l) of Example 39A and 8.10 mg (0.08 mmol; solution: 0.08 mol/l) of triethylamine.

Workup

  1. additionThe amount added

Sources & evidence

ORD record
ord-2bd15a287e634d3393e225c21246b763
Source dataset
uspto-grants-2005_08
Patent number
US06936609B2

Reaction notes

Loading…