HCID 22329559, compound → HCID 22329523, compound

Participants

Reaction Steps

To a solution of 5-fluoro-2-(2-fluoro-5-nitrophenyl)pyridine (1.23 g) in ethanol (70 ml) and dichloromethane (30 ml) was added platinum(IV) oxide (150 mg) and the mixture shaken on a Parr hydrogenation apparatus under an atmosphere of hydrogen at 45 psi for 1 h. Filtration and evaporation of the filtrate afforded 4-fluoro-3-(5-fluoropyridin-2-yl)phenylamine: MS (ES+) m/z 207.

Provenance & Evidence