2-Amino-2-methyl-1-propanol → N-(2-Hydroxy-1,1-dimethylethyl)-5-chloro-2-pyridinecarboxamide

HRID 586806Notes

Reaction equation

HRID 586806 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([OH:10])=O)=[N:6][CH:7]=1.[NH2:11][C:12]([CH3:16])([CH3:15])[CH2:13][OH:14]>>[OH:14][CH2:13][C:12]([NH:11][C:8]([C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][N:6]=1)=[O:10])([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 118072-Amino-2-methyl-1-propanolHCID 27628725-Chloro-2-picolinic acid

Product 1

HCID 9964611N-(2-Hydroxy-1,1-dimethylethyl)-5-chloro-2-pyridinecarboxamide

Procedure

The title compound was prepared by the same method as that described in Example 26, using 5-chloro-2-pyridinecarboxylic acid obtained in Example 40-2) and 2-amino-2-methyl-1-propanol.

Sources & evidence

ORD record
ord-2364353a35c34c8f89ba3317789d58c8
Source dataset
uspto-grants-2005_08
Patent number
US06936736B2

Reaction notes

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