Piperazine → 3-[(4-(Piperazin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide

HRID 587146Notes

Reaction equation

HRID 587146 reaction equation
[N:1]1([C:7]2[N:12]=[CH:11][N:10]=[C:9]([NH:13][C:14]3[CH:15]=[C:16]([CH2:20][S:21]([NH2:24])(=[O:23])=[O:22])[CH:17]=[CH:18][CH:19]=3)[N:8]=2)[CH2:6][CH2:5]C[CH2:3][CH2:2]1.ClC1N=CN=C(NC2C=C(CS(N)(=O)=O)C=CC=2)[N:27]=1.N1CCNCC1>>[N:1]1([C:7]2[N:12]=[CH:11][N:10]=[C:9]([NH:13][C:14]3[CH:15]=[C:16]([CH2:20][S:21]([NH2:24])(=[O:22])=[O:23])[CH:17]=[CH:18][CH:19]=3)[N:8]=2)[CH2:6][CH2:5][NH:27][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 4837PiperazineHCID 601971013-[(4-(Piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamideHCID 866798223-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Product 1

HCID 601971053-[(4-(Piperazin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide

Procedure

B11 was prepared following the procedure reported for B1 using A1 and piperazine. MS (ES) C14H19N7O2S requires: 349. found: 350 (M+H)+.

Workup

  1. customB11 was prepared

Sources & evidence

ORD record
ord-ca544ee631f9440493d3ef460bcd2779
Source dataset
uspto-grants-2016_01
Patent number
US09226929B2

Reaction notes

Loading…