6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride → 3-[(4-(5H-Pyrrolo[3,4-d]pyrimidin-6(7H)-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide

Participants

Role	Name	HCID	Charge
Reactant	6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride	HCID 54758847	—
Reactant	3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide	HCID 86679822	—
Product	3-[(4-(5H-Pyrrolo[3,4-d]pyrimidin-6(7H)-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide	HCID 60197810	—

Reaction Steps

B50 was prepared following the general procedure reported for B10 using A1 and 6,7-dihydro-5H-pyrrolo[3,4-d]pyrim idine hydrochloride; yield: 205.4 mg (53%), colorless amorphous solid. MS (ES) C16H16N8O2S requires: 384. found: 385 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09226929B2
Source dataset	uspto-grants-2016_01
ORD ID	ord-4219b9baea0b4cfdb035e4c0fe1893fd
Source note	uspto-grants-2016_01