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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587965Generated: October 30, 2026

Methyl 3-(6-bromo-3-cyano-2-methylhexan-3-yl)benzoate → Methyl 3-(2-((4-cyano-4-(3-(methoxycarbonyl)phenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

https://huagongshe.com/reaction/587965

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(6-bromo-3-cyano-2-methylhexan-3-yl)benzoateHCID 59419923—
ReactantMethyl 3-(2-(methylamino)ethyl)benzoateHCID 59419935—
ProductMethyl 3-(2-((4-cyano-4-(3-(methoxycarbonyl)phenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoateHCID 25130992—

Reaction Steps

Reaction of 1r with 2d produced 3ap. MS found M+H=451. The oxalate salt of 3ap was recrystallized from methanol/ether; mp 129-136° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-f8b217307e754e4a800e57f913f955a4
Source noteuspto-grants-2016_01