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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587975Generated: October 30, 2026

Triethyl phosphite → methyl 2-(diethoxyphosphoryl)-propionate

https://huagongshe.com/reaction/587975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethyl phosphiteHCID 31215—
ReactantMethyl 2-bromopropionateHCID 95576—
Productmethyl 2-(diethoxyphosphoryl)-propionateHCID 11401826—

Reaction Conditions

Temperature110 °C

Reaction Steps

Methyl 2-bromopropionate (100 g, 0.60 mol) and triethylphosphite (109 g, 0.66 mol) were mixed, and the mixture was stirred at 110° C. for 2 days. The reaction mixture was dried under reduced pressure to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227949B2
Source datasetuspto-grants-2016_01
ORD IDord-365f9107df57404081fd4befcb9e8d3f
Source noteuspto-grants-2016_01