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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588051Generated: November 1, 2026

(4-Aminophenoxy)benzene → HCID 71496600, compound

https://huagongshe.com/reaction/588051

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Aminophenoxy)benzeneHCID 8764—
Reactant1-Benzyl-4-piperidylamineHCID 415852—
ReactantHCID 1419048HCID 1419048—
ReactantHCID 4548294HCID 4548294—
ProductHCID 71496600HCID 7149660077.8%

Reaction Steps

The title compound was prepared in the same manner as in Example 1, with the exception that 2-chloro-(N-4-phenoxyphenyl)nicotinamide of Preparation Example 6, instead of 2-chloro-(N-3-chlorophenyl)nicotinamide, and 4-phenoxyaniline, instead of 4-amino-1-benzylpiperidine, were used in the same molar amounts (Yield: 77.8%). 1H NMR (DMSO-d6) δ 10.50 (s, 1H), 10.33 (s, 1H), 8.35 (d, 1H), 8.25 (d, 1H), 7.69˜7.82 (m, 4H), 7.30˜7.46 (m, 4H), 6.88˜7.18 (m, 11H) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227955B2
Source datasetuspto-grants-2016_01
ORD IDord-ca9c723f1d634a71b4e5c7b50d7eca7c
Source noteuspto-grants-2016_01