Hydrochloric Acid → HCID 118272496, compound

HRID 588128Notes

Reaction equation

[CH3:1][C:2]([CH3:12])([CH3:11])[CH:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[NH2:4].Cl.[O-:14][C:15]#[N:16].[K+]>>[CH3:1][C:2]([CH3:12])([CH3:11])[CH:3]([NH:4][C:15]([NH2:16])=[O:14])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 37525352,2-Dimethyl-1-phenylpropan-1-amine

HCID 11378442Potassium cyanate

Product 1

HCID 118272496HCID 118272496, compound

Procedure

In a manner simnilar to that described for Intermediate 16B, 2,2-dimethyl-1-phenylpropan-1-amine was reacted with HCl and potassium cyanate to provide 1-(2,2-dimethyl-1-phenylpropyl)urea. MS: [M+H]+ m/z 207.

Sources & evidence

ORD record: ord-fbef917659c840ce9737e5eec760ce18
Source dataset: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09226922B2

Reaction notes

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