5-(6-methyl-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)pyridine-2-carboxylic acid → tert-butyl (3R)-3-[(3-chloropyridin-2-yl){[5-(6-methyl-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)pyridin-2-yl]carbonyl}amino]piperidine-1-carboxylate

Participants

Reaction Steps

Prepared according to General Procedure A and C starting from Preparation 1 tert-butyl (3R)-3-[(3-chloropyridin-2-yl)amino]piperidine-1-carboxylate (3.22 g, 10.3 mmol) and Preparation 8 5-(6-methyl-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)pyridine-2-carboxylic acid (2.51 g, 9.83 mmol) to provide 2.33 g (43%) of the product as a solid.

Provenance & Evidence