Pyrrolidine → 6-Bromo-2-(3-methoxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridine

HRID 588462Notes

Reaction equation

HRID 588462 reaction equation
N1CCC[CH2:2]1.[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)[N:15]=2)[CH:12]=1>>[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:17][CH2:2][CH:20]([O:19][CH3:18])[CH2:21]3)[N:15]=2)[CH:12]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 717438774-(6-Bromo-[1,2,4]triazolo[1,5-A]pyridin-2-YL)morpholine

Product 1

HCID 894645726-Bromo-2-(3-methoxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridine

Procedure

Using pyrrolidine, this compound was prepared following the same method as for the synthesis of 6-bromo-2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridine Brown solid (2.5 g, 47%). MS: m/z=298 (M+H+).

Workup

  1. customthis compound was prepared

Sources & evidence

ORD record
ord-0dde767e8a28450fa4726527d739d956
Source dataset
uspto-grants-2016_01
Patent number
US09227970B2

Reaction notes

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