Hydrochloric Acid → HCID 67395342, compound

Participants

Reaction Conditions

Reaction Steps

To a vial containing 5-[(1R)-1-{[(S)-tert-butylsulfinyl]amino}ethyl]thiophene-2-carboxylate (0.050 g, 0.15 mmol) was added hydrochloric acid (3 mL, 12.0 mmol, 4.0 M of in 1,4-dioxane). This mixture was capped and heated at 60° C. for 2 h, after which it was evaporated to dryness to afford (R)-5-(1-aminoethyl)thiophene-2-carboxylic acid hydrochloride as a white solid. LC-MS: (FA) ES+ 172.

Provenance & Evidence