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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 589027Generated: October 31, 2026

Bromine → 2-Bromo-1-(1,3-thiazol-2-yl)ethan-1-one

https://huagongshe.com/reaction/589027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
Reactant2-AcetylthiazoleHCID 520108—
SolventAcetic AcidHCID 176—
Product2-Bromo-1-(1,3-thiazol-2-yl)ethan-1-oneHCID 2795212100%

Reaction Conditions

Temperature100 °C

Reaction Steps

Bromine (70 μL, 1 mmol) was added to a mixture of 1-(1,3-thiazol-2-yl)ethanone (200 mg, 2 mmol) in AcOH (5 mL). The reaction mixture was stirred at 100° C. for 30 min. and was concentrated under reduced pressure to give 2-bromo-1-(1,3-thiazol-2-yl)ethanone as an oil (100%) used as crude.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227985B2
Source datasetuspto-grants-2016_01
ORD IDord-db14e5c46bff42a58ffb9bd26c288d77
Source noteuspto-grants-2016_01