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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 589315Generated: October 31, 2026

Fexofenadine Hydrochloride → Fexofenadine

https://huagongshe.com/reaction/589315

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFexofenadine HydrochlorideHCID 63002—
ReactantHCID 178435160HCID 178435160—
SolventCyclohexaneHCID 8078—
ProductFexofenadineHCID 3348—

Reaction Steps

Cyclohexane is poured into the microencapsulation reactor. Then, under continuous stirring, fexofenadine HCl, ethylcellulose (EC) and polyethylene are added. The mixture is heated and then cooled down. Microcapsules are recovered, and then washed (one or more times), filtered, and dried over night (about 16 h) in a fume hood or in a hood at 40° C. The powder is sieved through a 300 μm opening sieve.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233105B2
Source datasetuspto-grants-2016_01
ORD IDord-0e6b7d98823d4d1ab0247764f0946649
Source noteuspto-grants-2016_01