HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Dimethylamino)benzoyl chloride → 4-tert-Butyl-N-{3-[6-(3,6-dihydro-2H-thiopyran-4yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-5-fluor-2-methyl-phenyl}-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Dimethylamino)benzoyl chloride | HCID 4400782 | — |
| Reactant | 2-tert-Butylbenzoyl chloride | HCID 13767186 | — |
| Reactant | 3-[6-(3,6-Dihydro-2H-thiopyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-5-fluoro-2-methyl-phenylamine | HCID 86730991 | — |
| Product | 4-tert-Butyl-N-{3-[6-(3,6-dihydro-2H-thiopyran-4yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-5-fluor-2-methyl-phenyl}-benzamide | HCID 71230693 | — |
Reaction Steps
Example 24 was prepared analogue to Example 15 by replacing Intermediate 6 with Intermediate 16 and 4-dimethyaminobenzoyl chloride with tert-butylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233111B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-5956685ecc0749dfb006d1eeff8a1947 |
| Source note | uspto-grants-2016_01 |