反应详情

温度

60 °C

A mixture of 5-fluoro-3-methylbenzothiophene-2-sulfonic acid (230 mg, 0.93 mmol) in POCl3 (5 mL) was heated at 60° C. over night. The POCl3 was evaporated and the crude product was dissolved in CH2Cl2 and washed with water. The organic phase was dried and evaporated to give 0.23 g (93%) of the title compound.

1. customThe POCl3 was evaporated
2. dissolutionthe crude product was dissolved in CH2Cl2
3. washwashed with water
4. customThe organic phase was dried
5. customevaporated