참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 5-Fluoro-3-methylbenzothiophene-2-sulfonic acid | HCID 17855410 | — |
| 생성물 | 5-Fluoro-3-methylbenzo[b]thiophene-2-sulphonyl chloride | HCID 2774586 | 93% |
반응 단계
A mixture of 5-fluoro-3-methylbenzothiophene-2-sulfonic acid (230 mg, 0.93 mmol) in POCl3 (5 mL) was heated at 60° C. over night. The POCl3 was evaporated and the crude product was dissolved in CH2Cl2 and washed with water. The organic phase was dried and evaporated to give 0.23 g (93%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09233946B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_01 |
|---|
| ORD ID | ord-fe9222313f924dadb315294cf65a9697 |
|---|
| 출처 메모 | uspto-grants-2016_01 |
|---|
