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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 589725Generated: October 30, 2026

4′-(Trifluoromethyl)[1,1′-biphenyl]-3-sulfonyl chloride → HCID 178527498, compound

https://huagongshe.com/reaction/589725

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4′-(Trifluoromethyl)[1,1′-biphenyl]-3-sulfonyl chlorideHCID 3789336—
ReactantHCID 178507542HCID 178507542—
ProductHCID 178527498HCID 17852749864.2%

Reaction Steps

The product was synthesized according to General Procedure 1, described in Example 1, starting with {3-[4-(trifluoromethyl)phenyl]phenyl}sulfonyl chloride (17.6 mg, 0.055 mmol) and 5-(3-amino-phenyl)tetrazole (8 mg, 0.05 mmol) yielding 14.3 mg (64%) of the title compound. MS (ESI+) calcd for C20H14F3N5O2S 445.082030, found 445.081660.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233946B2
Source datasetuspto-grants-2016_01
ORD IDord-05fccb7844bb4756bda3fa76168df1cb
Source noteuspto-grants-2016_01