HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178527493, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 5-(Isoxazol-3-yl)thiophene-2-sulfonyl chloride | HCID 2797180 | — |
| Reactant | HCID 178507542 | HCID 178507542 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178527493 | HCID 178527493 | 54% |
Reaction Steps
The product was prepared according to General Procedure 1, described in Example 1, with 5-isoxazol-3-ylthiophene-2-sulfonyl chloride (13.7 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol) and with a slightly modified purification method using 0.1% TFA in water as buffet. The title compound was obtained in 54% yield (11.1 mg). MS (ESI+) calcd mass for C14H10N6O3S2 374.025580, found 374.025400.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233946B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-22b160f8381945769da26cac45653170 |
| Source note | uspto-grants-2016_01 |