2,3-Dichlorobenzene-1-sulfonyl chloride → HCID 178527502, compound

HRID 589736Notes

Reaction equation

HRID 589736 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9](Cl)(=[O:11])=[O:10].[NH2:13][C:14]1[CH:15]=[C:16]([C:20]2[NH:24][N:23]=[N:22][N:21]=2)[CH:17]=[CH:18][CH:19]=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([C:20]2[NH:24][N:23]=[N:22][N:21]=2)[CH:15]=1)(=[O:11])=[O:10]

Participants

3

Reactant 2

HCID 27342222,3-Dichlorobenzene-1-sulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527502HCID 178527502, compoundYield 74%

Procedure

The product was prepared according to General Procedure 6, described in Example 65, with 2,3-dichlorobenzenesulfonyl chloride (13.5 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol). The title compound was obtained in 74% yield (13.7 mg). MS (ESI+) calcd mass for C13H9Cl2N5O2S 368.985401, found 368.984901.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-b90f3b1befd84dc2991beb6a8ca42ac3
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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