2,5-Dichlorobenzenesulfonyl chloride → HCID 178527508, compound

HRID 589737Notes

Reaction equation

HRID 589737 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9](Cl)(=[O:11])=[O:10].[NH2:13][C:14]1[CH:15]=[C:16]([C:20]2[NH:24][N:23]=[N:22][N:21]=2)[CH:17]=[CH:18][CH:19]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([C:20]2[NH:24][N:23]=[N:22][N:21]=2)[CH:15]=1)(=[O:11])=[O:10]

Participants

3

Reactant 2

HCID 794012,5-Dichlorobenzenesulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527508HCID 178527508, compoundYield 45%

Procedure

The product was prepared according to General Procedure 6, described in Example 65, with 2,5-dichlorobenzenesulfonyl chloride (13.5 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol). The title compound was obtained in 45% yield (8.3 mg). MS (ESI+) calcd mass for C13H9Cl2N5O2S 368.985401, found 368.985761.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-082e63f2f6ca405785e163f0f39d5066
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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