7-Chloro-2,1,3-benzoxadiazole-4-sulfonyl chloride → HCID 178527503, compound

HRID 589742Notes

Reaction equation

HRID 589742 reaction equation
[Cl:1][C:2]1[C:10]2[C:6](=[N:7][O:8][N:9]=2)[C:5]([S:11](Cl)(=[O:13])=[O:12])=[CH:4][CH:3]=1.[NH2:15][C:16]1[CH:17]=[C:18]([C:22]2[NH:26][N:25]=[N:24][N:23]=2)[CH:19]=[CH:20][CH:21]=1>>[Cl:1][C:2]1[C:10]2=[N:9][O:8][N:7]=[C:6]2[C:5]([S:11]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([C:22]3[NH:26][N:25]=[N:24][N:23]=3)[CH:17]=2)(=[O:13])=[O:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6125157-Chloro-2,1,3-benzoxadiazole-4-sulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527503HCID 178527503, compoundYield 52%

Procedure

The product was prepared according to General Procedure 6, described in Example 65, with 4-chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole (13.9 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol). The title compound was obtained in 52% yield (9.8 mg). MS (ESI+) calcd mass for C13H8ClN7O3S 377.009786, found 377.010126.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-6281a7f6ac884c3aa4f1bb83a51f821b
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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