3-Aminobenzoic Acid → HCID 56942025, compound

HRID 589747Notes

Reaction equation

HRID 589747 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([S:12](Cl)(=[O:14])=[O:13])=[CH:9][CH:8]=1.[NH2:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][CH:25]=1)[C:20]([OH:22])=[O:21]>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([S:12]([NH:16][C:17]2[CH:18]=[C:19]([CH:23]=[CH:24][CH:25]=2)[C:20]([OH:22])=[O:21])(=[O:14])=[O:13])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 74193-Aminobenzoic AcidHCID 27372315-(2-Pyridyl)thiophene-2-sulfonyl chloride

Product 1

HCID 56942025HCID 56942025, compoundYield 18%

Procedure

The product was prepared according to General Procedure 6, described in Example 65, with 5-(2-pyridyl)thiophene-2-sulfonyl chloride (13.5 mg, 0.055 mmol) and 3-aminobenzoic acid (6.9 mg, 0.050 mmol). The title compound was obtained in 18% yield (3.2 mg). MS (ESI+) calcd mass for C16H12N2O4S2 360.023848, found 360.023668.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-71dc1035e31d4ab985f28d1f1469a9d0
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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