3-Aminobenzoic Acid → HCID 56942167, compound

HRID 589753Notes

Reaction equation

HRID 589753 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[S:10](Cl)(=[O:12])=[O:11].[NH2:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18]([OH:20])=[O:19]>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[S:10]([NH:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18]([OH:20])=[O:19])(=[O:12])=[O:11]

Participants

3

Reactant 2

HCID 74193-Aminobenzoic AcidHCID 27763331-Benzothiophene-2-sulfonyl chloride

Product 1

HCID 56942167HCID 56942167, compoundYield 41%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, with 1-benzothiophene-2-sulfonyl chloride (12.8 mg, 0.055 mmol) and 3-aminobenzoic acid (6.9 mg, 0.050 mmol). The title compound was obtained in 41% yield (8.9 mg). MS (ESI+) calcd mass for C15H11NO4S2 333.012949, found 333.014269.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-41ba914249fb4ce2a675e9151cde0571
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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