HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-{[(5-Methyl-1-benzothiophen-2-yl)sulfonyl]amino}benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Aminobenzoic Acid | HCID 7419 | — |
| Reactant | 5-Methyl-1-benzothiophene-2-sulfonyl chloride | HCID 2794771 | — |
| Product | 3-{[(5-Methyl-1-benzothiophen-2-yl)sulfonyl]amino}benzoic acid | HCID 56942170 | 66% |
Reaction Steps
The product was prepared according to General Procedure 6, described in Example 65, with 5-methylbenzothiophene-2-sulfonyl chloride (30.0 mg, 0.12 mmol), pyridine (49 μL, 0.61 mmol) and 3-aminobenzoic acid (16.7 mg, 0.10 mmol). The title compound was obtained in 66% yield (23 mg). MS (ESI+) calcd mass for C16H13NO4S2 347.028599, found 347.029559.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233946B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-43f0009af29b4f1eb3930f4bc13f82ac |
| Source note | uspto-grants-2016_01 |