5-(Benzenesulfonyl)thiophene-2-sulfonyl chloride → HCID 178527510, compound

HRID 589802Notes

Reaction equation

HRID 589802 reaction equation
[C:1]1([S:7]([C:10]2[S:14][C:13]([S:15](Cl)(=[O:17])=[O:16])=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:19][C:20]1[CH:21]=[C:22]([C:26]2[NH:30][N:29]=[N:28][N:27]=2)[CH:23]=[CH:24][CH:25]=1>>[C:1]1([S:7]([C:10]2[S:14][C:13]([S:15]([NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]4[NH:30][N:29]=[N:28][N:27]=4)[CH:21]=3)(=[O:17])=[O:16])=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 5808775-(Benzenesulfonyl)thiophene-2-sulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527510HCID 178527510, compoundYield 40%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, with 5-benzenesulfonyl-thiophene-2-sulfonyl chloride (17.7 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8.0 mg, 0.050 mmol). The title compound was obtained in 40% yield (8.9 mg). MS (ESI+) calcd mass for C17H13N5O4S3 447.012966, found 447.013676.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-78ae26d1a32d47cfa5d747cd3a95730a
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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