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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590566Generated: October 25, 2026

Ethyl Acetoacetate → HCID 118358749, compound

https://huagongshe.com/reaction/590566

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetoacetateHCID 8868—
Reactant2-Chloro-4-fluorobenzaldehydeHCID 145024—
Reactant2-Chloro-3-fluorobenzaldehydeHCID 14944905—
ReactantMethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylateHCID 89995948—
ProductHCID 118358749HCID 118358749—

Reaction Steps

Compound C-1 was prepared in analogy to compound C by using ethyl acetoacetate and 2-chloro-3-fluorobenzaldehyde instead of methyl acetoacetate and 2-chloro-4-fluorobenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233978B2
Source datasetuspto-grants-2016_01
ORD IDord-c8c60468242641d59080dd20d745d105
Source noteuspto-grants-2016_01