反应详情

A mixture of {3-bromothieno[2,3-b]pyridin-2-yl}methanol (14c) (394 mg, 1.61 mmol) and manganese (II) oxide (1.4 g, 16.1 mmol) in dichloromethane (10 mL) was stirred for 20 hours, filtrated and evaporated to dryness to give the desired aldehyde (14d) without further purification (270 mg, 1.12 mmol, 70%).

1. filtrationfiltrated
2. customevaporated to dryness