HuagongsheHuagongshe Chemistry Print Report · For research reference only
{3-Bromothieno[2,3-b]pyridin-2-yl}methanol → 3-Bromothieno[2,3-b]pyridine-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {3-Bromothieno[2,3-b]pyridin-2-yl}methanol | HCID 70855402 | — |
| Catalyst | Manganese oxide | HCID 160959 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Bromothieno[2,3-b]pyridine-2-carbaldehyde | HCID 82387204 | — |
Reaction Steps
A mixture of {3-bromothieno[2,3-b]pyridin-2-yl}methanol (14c) (394 mg, 1.61 mmol) and manganese (II) oxide (1.4 g, 16.1 mmol) in dichloromethane (10 mL) was stirred for 20 hours, filtrated and evaporated to dryness to give the desired aldehyde (14d) without further purification (270 mg, 1.12 mmol, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09238026B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-191ed37298734886a2d09e97eaf0f626 |
| Source note | uspto-grants-2016_01 |