Methylamine → HCID 117821166, compound

Participants

Reaction Conditions

Reaction Steps

Methanamine (0.124 mL, 0.99 mmol) in EtOH was added to a solution of 2,4-dichloro-6-((cyclopropylmethoxy)methyl)pyrimidine (77 mg, 0.33 mmol) in acetonitrile (6 mL). The mixture was stirred at 0° C. for 30 minutes. The mixture was concentrated and the residue was purified by preparative HPLC give the title compound, 42 mg (56%).

Provenance & Evidence