Sodium sulfate decahydrate → (2-Isopropyl-4-methyl-1,3-thiazol-5-yl)methanol

Participants

Reaction Conditions

Reaction Steps

To a solution of ethyl 2-isopropyl-4-methyl-1,3-thiazole-5-carboxylate (2.42 g) in THF (50 mL) was added lithium aluminum hydride (0.431 g) at 0° C. The mixture was stirred at 0° C. under argon atmosphere for 1 h. To the mixture was added sodium sulfate decahydrate and the mixture was stirred for 10 min. The precipitate was filtered off through celite and the filtrate was concentrated in vacuo to give the title compound (1.9 g).

Provenance & Evidence