反应详情

温度

0 °C

To ethyl 4-chloro-3-oxobutanoate (5.77 mL) was added conc.H2SO4 (15.03 mL) at 0° C. Then to the mixture was added 2-methylbenzene-1,3-diol (5.0 g) in several portions at 0° C. The mixture was stirred at 0° C. for 30 min. The mixture was warmed to room temperature for 1.5 h. The reaction mixture was poured into water under stirring at 0° C. The precipitate was collected by filtration and washed with water to give the title compound (8.58 g).

1. customat 0° C
2. temperatureThe mixture was warmed to room temperature for 1.5 h
3. stirringunder stirring at 0° C
4. filtrationThe precipitate was collected by filtration
5. washwashed with water