Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 5918Generated: October 29, 2026

Formaldehyde → 3-(Hydroxymethyl)benzoselenazolinone

https://huagongshe.com/reaction/5918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantMethanolHCID 887—
ReactantBenzoselenazoleHCID 136087—
SolventWaterHCID 962—
Product3-(Hydroxymethyl)benzoselenazolinoneHCID 86747228—

Reaction Conditions

Temperature40 °C

Reaction Steps

2 grams (0.01 mol) of benzoselenazoline, 2 cm3 (0.02 mol) of aqueous formaldehyde solution and 2 cm3 of methanol are introduced into a ground-necked flask. The mixture is brought to reflux two hours. After cooling to 40° C. 20 cm3 of water are added. The mixture is allowed to cool and the product is drained, washed with water, dried and recrystallized in cyclohexane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05246951
Source datasetuspto-grants-1993_09
ORD IDord-5d28e8e0676841e598914b8d0977a4cb
Source noteuspto-grants-1993_09