Trifluoroacetic acid → HCID 89738583, compound

Participants

Reaction Steps

tert-butyl(1R,2S,3R,4S)-3-carbamoyl-7-oxabicyclo[2.2.1]heptan-2-ylcarbamate (14) (40 mg, 0.156 mmol) was taken in DCM and cooled to 0° C. when TFA (10 eq) was added and the reaction mixture was then stirred at rt for 3-4 h when TLC confirmed completion of reaction. TFA was removed and afforded the product (40 mg, quantitative) as a yellow oil.

Provenance & Evidence